Share with wechat scanning QR code < / P > < p > to friends and circle of friends < / P > < p > Beijing daily client & nbsp|& nbsp; Reporter Bai Bo < / P > < p > new crown vaccine booster injections have been launched in many places across the country; Sporadic local cases continue to appear everywhere; The temperature dropped sharply and the winter with active virus transmission is coming... The Tianjin forum with the theme of "meeting new challenges: Science and technology helps urban development and governance" was held before 2021. Zeng Guang, a famous epidemiologist and counselor of Beijing municipal government, attended the sub forum of "public health safety in the context of urban sustainable development", He accepted an exclusive interview with the client reporter of Beijing daily and answered a series of questions of public concern. He said that there is no doubt about the necessity of strengthening needle vaccination of the new crown vaccine. In order to improve the immune effect, sequential vaccination of the new crown vaccine can be considered. When to open the door and resume international exchanges is an issue that needs comprehensive consideration. If China adjusts its prevention and control strategy, the immune barrier needs to be more reliable. After the immune barrier is established, it does not mean that there are no new cases, but that the virus is not easy to spread < p > < / P > < p > booster injection may be directly called the "third injection" < / P > < p > Beijing daily client: now the booster injection of new crown vaccine has been widely launched in China. Winter is coming. What suggestions do you have for vaccination with booster needles < p > Zeng Guang: at present, the basic immunization procedures of different new crown vaccines at home and abroad need one, two and three injections. After several months of inoculation, there is a decline in antibodies to varying degrees, and we are faced with the problem of whether to give "booster injection". At present, the most vaccinated population in China is the inactivated vaccine with two immunization procedures. Generally, the antibody effect begins to decline after 3 months and drops significantly after 6 months. Among them, the effect of two injections of basic immunization for the elderly over 60 years old is not as good as that for the young, and the antibody decreases faster. Under the current situation of epidemic prevention and control, priority must be given to vaccination < p > but I think that the new crown vaccine for the elderly can not be called booster injection, but should be called the third injection of basic immunization. How to put it? With the evaluation of the real effect of vaccination, it is found that the two needle basic immunization program originally designed is not enough to achieve the ideal immune effect, so it can be modified to the three needle basic immunization program. In the past, two needles were designed at the beginning. Now it is time to put forward the idea of adding a third needle. It can be started from the elderly and people in high-risk industries, and then further extended to other people < p > this has several advantages. The first is to seek truth from facts. For domestic inactivated vaccine, the need for the third injection should be put forward in time. The second is to tell people that vaccination needs to be generally strengthened. The third is to avoid disputes with the World Health Organization. If the booster needle is called all the time, it seems that the basic immunization has been completed and needs to be strengthened again. Although China has provided more than 1.25 billion doses of vaccine to countries all over the world, in this way, the World Health Organization will say to all countries that have increased booster injections that your basic immunization has been completed, you should stop the booster injections and give the vaccine to those countries that lack vaccines. If China has not completed the three needle basic immunization procedure, it is another matter. I think it is scientific, reasonable and feasible to modify the basic immunization procedure < p > Beijing daily client: can the reinforcing needle or the third needle achieve the desired effect < p > Zeng Guang: there is no doubt about the effect of reinforcing needle. It will certainly play a great role. But how can vaccination work better? For example, as the third injection of basic immunization, homologous vaccines can be continued. The vaccines are sufficient and easy for vaccinators to accept. But is the effect homologous or heterologous? There have been many studies at home and abroad, and it is generally believed that the effect of heterologous vaccination is very good. For example, I don't inactivate the third injection, but I do mRNA. Such experimental results have been obtained, and the effect is obviously better than homologous inoculation. However, the advantages of homologous inoculation can not be denied < p > the technical term of heterologous vaccination is called sequential vaccination. For example, polio vaccine is now a sequential vaccination. The first two times can be oral attenuated vaccine, and the last two times can be inactivated vaccine. The concept of sequential vaccination should be made clear to the people < p > open the door? China's immune barrier is not reliable < / P > < p > Beijing daily client: Although the development of the global epidemic is still complicated and confusing, and the epidemic situation in many countries also tends to deteriorate, many countries are ready to open their doors and resume wider international exchanges. As a country enjoying the most dividends from epidemic prevention and control, when China can open its doors is also one of the most concerned topics in the near future. What do you think of this issue < p > Zeng Guang: This is a very important issue of concern to the whole people < p > China's epidemic prevention and control adopts a national system dominated by the state. In this case, we deal with relevant issues not only from the perspective of science and public health, but also from the perspective of political, economic and social stability. When can I open the door? This issue still needs to be comprehensively considered by the state < p > although many western countries have proposed to open their doors and resume international exchanges, they may not have a foundation in their hearts. In the face of the epidemic situation, the scientific dimension of western countries is extremely limited. First of all, they have no ability to "clear" like China. After the first three months of the early epidemic, they have no chance to clear again. What factors will affect them later? It is not only scientific factors, but also affected by their laws, social systems, party competition and economic development < p > what is my opinion? Let's first look at the countries that open their doors, what they will bring in the end, and what their specific operations are. Like Britain, Israel, Denmark and Singapore, they say they want to open the door. In fact, they also touch the stone to cross the river. They open it step by step, and when the door is opened, it can be closed < p > I think the immune barrier in China is not firm. If we want to adjust our prevention and control strategy, we need to lay a solid foundation < p > in addition, we should see that the urgency of China's opening up is not as great as that of western countries, and China is still enjoying dividends. If this dividend disappears, I think we will see the decisive decision of our government < p > establishing an immune barrier is not because the virus is not popular < / P > < p > Beijing daily client: how can it be regarded as establishing an "immune barrier" < p > Zeng Guang: of course, the immune barrier can be established, but the establishment of the immune barrier is not like what some people think, and the virus is not popular ?
2023-03-22 10:04:45